|Sample Requirement||Turnaround Time|
|Serum||Same Working Day|
Total protein, albumin and globulin estimations are useful in the assessment of general bodily condition, nutritional status and the response to infectious or parasitic disease.
Total protein may increase with haemoconcentration/dehydration or increased protein production (chronic inflammation, neoplasia (eg monoclonal gammopathy)).
Total protein may decrease following increased loss (protein-losing enteropathy or glomerulopathy, following severe blood loss, or sequestration in cavitary effusions), increased blood volume (overhydration) or decreased production (inanition, advanced hepatic disease, malabsorption, reduced production secondary to an acute phase inflammatory protein response).
Albumin concentration increases in excited horses and those suffering from haemoconcentration/dehydration. Albumin will also be higher in heparinized plasma samples than serum.
Albumin will decrease with overhydration, decreased production (inanition, advanced hepatic disease, malabsorption, reduced production secondary to an acute phase inflammatory protein response), and increased loss (protein-losing enteropathy or glomerulopathy, following severe blood loss, or sequestration in cavitary effusions)
Total globulin may be raised due to increased production of alpha-globulins (acute phase proteins), beta-globulins (inflammation, liver disease, endoparasitism) and gamma globulins (chronic antigenic stimulation associated with infection), Some forms of neoplasia (lymphoma/leukaemia, myeloma) may cause monoclonal gammopathies in the beta-globulin or gamma globulin ranges.
|Age||Total Protein Range (g/l)||Albumin Range (g/l)||Globulin Range (g/l)|
|Adult Non-Thoroughbred Horses||53-73||29-41||18-38|
|Neonatal Thoroughbred Foals (24-48hrs old)||41-66||25-35||15-36|
|Older Thoroughbred Foals (approx. 3 weeks old)||42-66||26-37||15-33|
|Yearling Thoroughbred Horses||52-64||31-38||18-29|
|Two-Year-Old Thoroughbred Horses in Training||59-66||35-39||21-28|
|Three-Year-Old Thoroughbred Horses in Training||58-67||35-40||22-29|
|Adult Thoroughbred Horses at Stud||65-75||34-38||29-39|